Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice

In the present study, we investigated the role of Nrf2 in airway immune responses induced by diesel exhaust (DE) inhalation in mice. C57BL/6J Nrf2(+/+) and Nrf2(−/−) mice were exposed to DE or clean air for 8 h/day and 6 days/week for 4 weeks. After DE exposure, the number of neutrophils and macroph...

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Bibliografske podrobnosti
izdano v:Biomedicines
Main Authors: Li, Ying-Ji, Shimizu, Takako, Shinkai, Yusuke, Ihara, Tomomi, Sugamata, Masao, Kato, Katsuhito, Kobayashi, Maiko, Hirata, Yukiyo, Inagaki, Hirofumi, Uzuki, Makoto, Akimoto, Toshio, Umezawa, Masakazu, Takeda, Ken, Azuma, Arata, Yamamoto, Masayuki, Kawada, Tomoyuki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589508/
https://ncbi.nlm.nih.gov/pubmed/33096811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100443
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