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Peroxisome Proliferator-Activated Receptor α Activation Is Not the Main Contributor to Teratogenesis Elicited by Polar Compounds from Oxidized Frying Oil

We previously reported that polar compounds (PO) in cooking oil are teratogenic and perturbed retinoic acid (RA) metabolism. Considering PO as a potent peroxisome proliferator-activated receptor α (PPARα) activator, this study aimed to investigate the role of PPARα in PO-induced teratogenesis and di...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Lin, Yu-Shun, Lin, Ting-Yi, Wu, Jia-Jiuan, Yao, Hsien-Tsung, Chang, Sunny Li-Yun, Chao, Pei-Min
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372526/
https://ncbi.nlm.nih.gov/pubmed/28264465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030510
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