Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

BACKGROUND: Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify integrated subtypes. METHODS: Tumor tissue from 425 patients with primary breast cancer from the Os...

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Publicat a:Breast Cancer Res
Autors principals: Aure, Miriam Ragle, Vitelli, Valeria, Jernström, Sandra, Kumar, Surendra, Krohn, Marit, Due, Eldri U., Haukaas, Tonje Husby, Leivonen, Suvi-Katri, Vollan, Hans Kristian Moen, Lüders, Torben, Rødland, Einar, Vaske, Charles J., Zhao, Wei, Møller, Elen K., Nord, Silje, Giskeødegård, Guro F., Bathen, Tone Frost, Caldas, Carlos, Tramm, Trine, Alsner, Jan, Overgaard, Jens, Geisler, Jürgen, Bukholm, Ida R. K., Naume, Bjørn, Schlichting, Ellen, Sauer, Torill, Mills, Gordon B., Kåresen, Rolf, Mælandsmo, Gunhild M., Lingjærde, Ole Christian, Frigessi, Arnoldo, Kristensen, Vessela N., Børresen-Dale, Anne-Lise, Sahlberg, Kristine K.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372339/
https://ncbi.nlm.nih.gov/pubmed/28356166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0812-y
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