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Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF

INTRODUCTION: Hypercoagulability in malignancy increases the risk of thrombosis, but is also involved in cancer progression. Experimental studies suggest that tissue factor (TF) and tissue factor pathway inhibitor (TFPI) are involved in cancer biology as a tumor- promoter and suppressor, respectivel...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Tinholt, Mari, Vollan, Hans Kristian Moen, Sahlberg, Kristine Kleivi, Jernström, Sandra, Kaveh, Fatemeh, Lingjærde, Ole Christian, Kåresen, Rolf, Sauer, Torill, Kristensen, Vessela, Børresen-Dale, Anne-Lise, Sandset, Per Morten, Iversen, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423106/
https://ncbi.nlm.nih.gov/pubmed/25882602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0548-5
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