DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis

BACKGROUND: Multiple factors, including interactions between genetic and environmental risks, are important in susceptibility to rheumatoid arthritis (RA). However, the underlying mechanism is not fully understood. This study was undertaken to evaluate whether DNA methylation can mediate the interac...

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Bibliografiska uppgifter
I publikationen:Arthritis Res Ther
Huvudupphovsmän: Meng, Weida, Zhu, Zaihua, Jiang, Xia, Too, Chun Lai, Uebe, Steffen, Jagodic, Maja, Kockum, Ingrid, Murad, Shahnaz, Ferrucci, Luigi, Alfredsson, Lars, Zou, Hejian, Klareskog, Lars, Feinberg, Andrew P., Ekström, Tomas J., Padyukov, Leonid, Liu, Yun
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372280/
https://ncbi.nlm.nih.gov/pubmed/28356135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1276-2
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