Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells

The (neo-) lacto series glycosphingolipids (nsGSLs) comprise of glycan epitopes that are present as blood group antigens, act as primary receptors for human pathogens and are also increasingly associated with malignant diseases. Beta-1, 3-N-acetyl-glucosaminyl-transferase 5 (B3GNT5) is suggested as...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alam, Shahidul, Anugraham, Merrina, Huang, Yen-Lin, Kohler, Reto S., Hettich, Timm, Winkelbach, Katharina, Grether, Yasmin, López, Mónica Núñez, Khasbiullina, Nailia, Bovin, Nicolai V., Schlotterbeck, Götz, Jacob, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371825/
https://ncbi.nlm.nih.gov/pubmed/28358117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45367
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