Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells

The (neo-) lacto series glycosphingolipids (nsGSLs) comprise of glycan epitopes that are present as blood group antigens, act as primary receptors for human pathogens and are also increasingly associated with malignant diseases. Beta-1, 3-N-acetyl-glucosaminyl-transferase 5 (B3GNT5) is suggested as...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Alam, Shahidul, Anugraham, Merrina, Huang, Yen-Lin, Kohler, Reto S., Hettich, Timm, Winkelbach, Katharina, Grether, Yasmin, López, Mónica Núñez, Khasbiullina, Nailia, Bovin, Nicolai V., Schlotterbeck, Götz, Jacob, Francis
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371825/
https://ncbi.nlm.nih.gov/pubmed/28358117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45367
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