SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation

The serum- and glucocorticoid-regulated kinase (SGK1) controls cell transformation and tumor progression. SGK1 affects mitotic stability by regulating the expression of RANBP1/RAN. Here, we demonstrate that SGK1 fluctuations indirectly modify the maturation of pre-miRNAs, by modulating the equilibri...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Rep
Main Authors: Dattilo, Vincenzo, D’Antona, Lucia, Talarico, Cristina, Capula, Mjriam, Catalogna, Giada, Iuliano, Rodolfo, Schenone, Silvia, Roperto, Sante, Bianco, Cataldo, Perrotti, Nicola, Amato, Rosario
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371792/
https://ncbi.nlm.nih.gov/pubmed/28358001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45361
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍