Regulation of the Functions of Natural Cytotoxicity Receptors by Interactions with Diverse Ligands and Alterations in Splice Variant Expression

The natural cytotoxicity receptor (NCR) family is constituted by NKp46, NKp44, and NKp30 in humans, which are expressed mainly on natural killer (NK) cells and are encoded by the ncr1, ncr2, and ncr3 genes, respectively. NCRs have classically been defined as activating receptors that trigger cytotox...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Pazina, Tatiana, Shemesh, Avishai, Brusilovsky, Michael, Porgador, Angel, Campbell, Kerry S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371597/
https://ncbi.nlm.nih.gov/pubmed/28424697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00369
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