Expression of NKp46 Splice Variants in Nasal Lavage Following Respiratory Viral Infection: Domain 1-Negative Isoforms Predominate and Manifest Higher Activity

The natural killer (NK) cell activating receptor NKp46/NCR1 plays a critical role in elimination of virus-infected and tumor cells. The NCR1 gene can be transcribed into five different splice variants, but the functional importance and physiological distribution of NKp46 isoforms are not yet fully u...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shemer-Avni, Yonat, Kundu, Kiran, Shemesh, Avishai, Brusilovsky, Michael, Yossef, Rami, Meshesha, Mesfin, Solomon-Alemayehu, Semaria, Levin, Shai, Gershoni-Yahalom, Orly, Campbell, Kerry S., Porgador, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309248/
https://ncbi.nlm.nih.gov/pubmed/28261217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00161
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