Peripheral venous congestion causes time‐ and dose‐dependent release of endothelin‐1 in humans

Endothelin‐1 (ET‐1) is a pivotal mediator of vasoconstriction and inflammation in congestive states such as heart failure (HF) and chronic kidney disease (CKD). Whether peripheral venous congestion (VC) increases plasma ET‐1 at pressures commonly seen in HF and CKD patients is unknown. We seek to ch...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Lin, Jeffrey, Chudasama, Neelesh, Hayashi, Yacki, Hawk, Christopher, Ramnauth, Sahadeo D., Wong, Ka Yuk, Harxhi, Ante, Onat, Duygu, Wakabayashi, Michiyori, Uriel, Nir, Jorde, Ulrich P., LeJemtel, Thierry H., Sabbah, Hani N., Demmer, Ryan T., Colombo, Paolo C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371548/
https://ncbi.nlm.nih.gov/pubmed/28320895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13118
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