A carregar...
Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases
In-frame premature termination codons (PTCs) (also referred to as nonsense mutations) comprise ~10% of all disease-associated gene lesions. PTCs reduce gene expression in two ways. First, PTCs prematurely terminate translation of an mRNA, leading to the production of a truncated polypeptide that oft...
Na minha lista:
| Publicado no: | Diseases |
|---|---|
| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5370586/ https://ncbi.nlm.nih.gov/pubmed/28367323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diseases4040032 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|