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Suppression of Nonsense Mutations As A Therapeutic Approach To Treat Genetic Diseases
Suppression therapy is a treatment strategy for genetic diseases caused by nonsense mutations. This therapeutic approach utilizes pharmacological agents that suppress translation termination at in-frame premature termination codons (PTCs) to restore translation of a full-length, functional polypepti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188951/ https://ncbi.nlm.nih.gov/pubmed/21976286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.95 |
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