Mechanism Underlying Linezolid-induced Thrombocytopenia in a Chronic Kidney Failure Mouse Model

OBJECTIVE: To investigate the relationship between renal function and linezolid (LZD)-induced thrombocytopenia and elucidate the underlying mechanism using a chronic renal disease (CRD) mouse model. MATERIALS AND METHODS: CRD was induced in 5-week-old male Institute of Cancer Research (ICR) mice by...

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Detalhes bibliográficos
Publicado no:J Pharmacol Pharmacother
Main Authors: Nishijo, Nao, Tsuji, Yasuhiro, Matsunaga, Kazuhisa, Kutsukake, Masahiko, Okazaki, Fumiyasu, Fukumori, Shiro, Kasai, Hidefumi, Hiraki, Yoichi, Sakamaki, Ippei, Yamamoto, Yoshihiro, Karube, Yoshiharu, To, Hideto
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370331/
https://ncbi.nlm.nih.gov/pubmed/28405130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/jpp.JPP_167_16
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