Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the overall relationship between cell commitment...

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Publicado en:eLife
Autores principales: Posfai, Eszter, Petropoulos, Sophie, de Barros, Flavia Regina Oliveira, Schell, John Paul, Jurisica, Igor, Sandberg, Rickard, Lanner, Fredrik, Rossant, Janet
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370188/
https://ncbi.nlm.nih.gov/pubmed/28226240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22906
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