Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice

Targeted mutant models are common in mechanistic toxicology experiments investigating the absorption, metabolism, distribution, or elimination (ADME) of chemicals from individuals. Key models include those for xenosensing transcription factors and cytochrome P450s (CYP). Here we investigated changes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Kumar, Ramiya, Mota, Linda C., Litoff, Elizabeth J., Rooney, John P., Boswell, W. Tyler, Courter, Elliott, Henderson, Charles M., Hernandez, Juan P., Corton, J. Christopher, Moore, David D., Baldwin, William S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2017
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370058/
https://ncbi.nlm.nih.gov/pubmed/28350814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174355
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