Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression

Male fertility disorders play a key role in half of all infertility cases. Reduction in testosterone induced by hypoxia might cause diseases in reproductive system and other organs. Hypoxic exposure caused a significant decrease of NRF1. Software analysis reported that the promoter region of steroid...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Wang, Xueting, Pan, Longlu, Zou, Zhiran, Wang, Dan, Lu, Yapeng, Dong, Zhangji, Zhu, Li
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369971/
https://ncbi.nlm.nih.gov/pubmed/28146428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14842
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