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GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF
The alternative reading frame protein (p14ARF/ARF) is a key determinant of cell fate, acting as a potent tumor suppressor through a p53/MDM2-dependent pathway or promoting apoptosis in a p53-independent manner. The ARF protein is mainly expressed in the nucleolus and sequestered by nucleophosmin (NP...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5369963/ https://ncbi.nlm.nih.gov/pubmed/27323397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9957 |
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