Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet’s disease susceptibility

We analyzed 1,900 Turkish Behçet’s disease cases and 1,779 controls genotyped with the Immunochip. The most significantly associated single nucleotide polymorphism (SNP) was rs1050502, a tag SNP for HLA-B*51. In the Turkish discovery set, we identified three novel loci, IL1A-IL1B, IRF8, and CEBPB-PT...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Takeuchi, Masaki, Mizuki, Nobuhisa, Meguro, Akira, Ombrello, Michael J., Kirino, Yohei, Satorius, Colleen, Le, Julie, Blake, Mary, Erer, Burak, Kawagoe, Tatsukata, Ustek, Duran, Tugal-Tutkun, Ilknur, Seyahi, Emire, Ozyazgan, Yilmaz, Sousa, Inês, Davatchi, Fereydoun, Francisco, Vânia, Shahram, Farhad, Abdollahi, Bahar Sadeghi, Nadji, Abdolhadi, Shafiee, Niloofar Mojarad, Ghaderibarmi, Fahmida, Ohno, Shigeaki, Ueda, Atsuhisa, Ishigatsubo, Yoshiaki, Gadina, Massimo, Oliveira, Sofia A., Gül, Ahmet, Kastner, Daniel L., Remmers, Elaine F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369770/
https://ncbi.nlm.nih.gov/pubmed/28166214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3786
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados