Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

Patients with Behçet's disease (BD) suffer from episodic inflammation often affecting the orogenital mucosa, skin, and eyes. To discover new BD-susceptibility loci, we performed a genome-wide association study (GWAS) of 779,465 SNPs with imputed genotypes in 1,209 Turkish BD patients and 1,278...

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Detalhes bibliográficos
Main Authors: Kirino, Yohei, Bertsias, George, Ishigatsubo, Yoshiaki, Mizuki, Nobuhisa, Tugal-Tutkun, Ilknur, Seyahi, Emire, Ozyazgan, Yilmaz, Sacli, F. Sevgi, Erer, Burak, Inoko, Hidetoshi, Emrence, Zeliha, Cakar, Atilla, Abaci, Neslihan, Ustek, Duran, Satorius, Colleen, Ueda, Atsuhisa, Takeno, Mitsuhiro, Kim, Yoonhee, Wood, Geryl M., Ombrello, Michael J., Meguro, Akira, Gül, Ahmet, Remmers, Elaine F., Kastner, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810947/
https://ncbi.nlm.nih.gov/pubmed/23291587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2520
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