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LC-MS/MS suggests that hole hopping in cytochrome c peroxidase protects its heme from oxidative modification by excess H(2)O(2)
We recently reported that cytochrome c peroxidase (Ccp1) functions as a H(2)O(2) sensor protein when H(2)O(2) levels rise in respiring yeast. The availability of its reducing substrate, ferrocytochrome c (Cyc(II)), determines whether Ccp1 acts as a H(2)O(2) sensor or peroxidase. For H(2)O(2) to serv...
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| Publicado no: | Chem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5369544/ https://ncbi.nlm.nih.gov/pubmed/28451256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03125k |
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