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Hole Hopping through Cytochrome P450
High-potential iron-oxo species are intermediates in the catalytic cycles of oxygenase enzymes. They can cause heme degradation and irreversible oxidation of nearby amino acids. We have proposed that there are protective mechanisms in which hole hopping from oxidized hemes through tryptophan/tyrosin...
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| Publicado no: | J Phys Chem B |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7219282/ https://ncbi.nlm.nih.gov/pubmed/32175746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b09414 |
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