DNA methylation alters transcriptional rates of differentially expressed genes and contributes to pathophysiology in mice fed a high fat diet

OBJECTIVE: Overnutrition can alter gene expression patterns through epigenetic mechanisms that may persist through generations. However, it is less clear if overnutrition, for example a high fat diet, modifies epigenetic control of gene expression in adults, or by what molecular mechanisms, or if su...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Zhang, Pili, Chu, Tianjiao, Dedousis, N., Mantell, Benjamin S., Sipula, Ian, Li, Lucy, Bunce, Kimberly D., Shaw, Patricia A., Katz, Liora S., Zhu, Jun, Argmann, Carmen, O'Doherty, Robert M., Peters, David G., Scott, Donald K.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369282/
https://ncbi.nlm.nih.gov/pubmed/28377872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.02.001
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