A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis

BACKGROUND: This study aimed to evaluate the efficacy of a high dose of oral tegafur-uracil (400 mg/m(2)) plus leucovorin with preoperative chemoradiation of locally advanced rectal cancer and to explore the impact of polymorphisms of cytochrome P 2A6 (CYP2A6), uridine monophosphate synthetase (UMPS...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Kim, Sun Young, Baek, Ji Yeon, Oh, Jae Hwan, Park, Sung Chan, Sohn, Dae Kyung, Kim, Min Ju, Chang, Hee Jin, Kong, Sun-Young, Kim, Dae Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369180/
https://ncbi.nlm.nih.gov/pubmed/28347333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-017-0800-5
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