Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer

BACKGROUND: Considerable variation in intravenous 5-fluorouracil (5-FU) metabolism can occur due to the wide range of dihydropyrimidine dehydrogenase (DPD) enzyme activity, which can affect both tolerability and efficacy. The oral fluoropyrimidine tegafur-uracil (UFT) is an effective, well-tolerated...

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Detalhes bibliográficos
Main Authors: Cellier, Patrice, Leduc, Bernard, Martin, Laurent, Vié, Brigitte, Chevelle, Christian, Vendrely, Véronique, Salemkour, Augustin, Carrie, Christian, Calais, Gilles, Burtin, Pascal, Campion, Loïc, Boisdron-Celle, Michèle, Morel, Alain, Berger, Virginie, Gamelin, Erick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070684/
https://ncbi.nlm.nih.gov/pubmed/21410976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-98
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