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INHIBITION OF INFLAMMATORY GENE TRANSCRIPTION BY IL-10 IS ASSOCIATED WITH RAPID SUPPRESSION OF LPS-INDUCED ENHANCER ACTIVATION(): Suppression of LPS-Induced Enhancer Activation by IL-10
IL-10 limits the magnitude of inflammatory gene expression following microbial stimuli and is essential to prevent inflammatory disease, however, the molecular basis for IL-10 mediated inhibition remains elusive. Using a genome-wide approach we demonstrate that inhibition of transcription is the pri...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5369026/ https://ncbi.nlm.nih.gov/pubmed/28213503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601781 |
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