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Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers
BACKGROUND: Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models. METHODS: Safety, tolerability, and plasma pharmacokinetics of singl...
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| Publicado no: | BMC Pharmacol Toxicol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368910/ https://ncbi.nlm.nih.gov/pubmed/28347318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0123-z |
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