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Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

Cancer cells reprogram their metabolism, altering both uptake and utilization of extracellular nutrients. We individually depleted amino acid nutrients from isogenic cells expressing commonly activated oncogenes to identify correspondences between nutrient supply and viability. In HME (human mammary...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Poursaitidis, Ioannis, Wang, Xiaomeng, Crighton, Thomas, Labuschagne, Christiaan, Mason, David, Cramer, Shira L., Triplett, Kendra, Roy, Rajat, Pardo, Olivier E., Seckl, Michael J., Rowlinson, Scott W., Stone, Everett, Lamb, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368412/
https://ncbi.nlm.nih.gov/pubmed/28297659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.054
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