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Genome Editing Reveals Glioblastoma Addiction to MicroRNA-10b
Glioblastoma (GBM) brain tumor remains among the most lethal and incurable human diseases. Oncogenic microRNA-10b (miR-10b) is strongly and universally upregulated in GBM, and its inhibition by antisense oligonucleotides (ASOs) reduces the growth of heterogeneous glioma cells; therefore, miR-10b rep...
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| Izdano u: | Mol Ther |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Gene & Cell Therapy
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368404/ https://ncbi.nlm.nih.gov/pubmed/28153089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.004 |
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