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Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis

Optimal drug proportions and mechanism deciphering of multicomponent drugs are critical for developing novel therapies to cope with complex diseases, such as stroke. In the present study, orthogonal experimental design was applied to explore the optimal proportion of the four component herbs in Huan...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Zhang, Qian, Wang, Junsong, Liao, Shanting, Li, Pei, Xu, Dingqiao, Lv, Yan, Yang, Minghua, Kong, Lingyi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368223/
https://ncbi.nlm.nih.gov/pubmed/28400733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00165
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