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Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis

Optimal drug proportions and mechanism deciphering of multicomponent drugs are critical for developing novel therapies to cope with complex diseases, such as stroke. In the present study, orthogonal experimental design was applied to explore the optimal proportion of the four component herbs in Huan...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Qian, Wang, Junsong, Liao, Shanting, Li, Pei, Xu, Dingqiao, Lv, Yan, Yang, Minghua, Kong, Lingyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368223/
https://ncbi.nlm.nih.gov/pubmed/28400733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00165
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