Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis

Optimal drug proportions and mechanism deciphering of multicomponent drugs are critical for developing novel therapies to cope with complex diseases, such as stroke. In the present study, orthogonal experimental design was applied to explore the optimal proportion of the four component herbs in Huan...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhang, Qian, Wang, Junsong, Liao, Shanting, Li, Pei, Xu, Dingqiao, Lv, Yan, Yang, Minghua, Kong, Lingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368223/
https://ncbi.nlm.nih.gov/pubmed/28400733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00165
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