Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis

Optimal drug proportions and mechanism deciphering of multicomponent drugs are critical for developing novel therapies to cope with complex diseases, such as stroke. In the present study, orthogonal experimental design was applied to explore the optimal proportion of the four component herbs in Huan...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Zhang, Qian, Wang, Junsong, Liao, Shanting, Li, Pei, Xu, Dingqiao, Lv, Yan, Yang, Minghua, Kong, Lingyi
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368223/
https://ncbi.nlm.nih.gov/pubmed/28400733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00165
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