Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1α to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells

Helicobacter pylori (H. pylori) is a human gastric pathogen that has been linked to the development of several gastric pathologies, such as gastritis, peptic ulcer, and gastric cancer. In the gastric epithelium, the bacterium modifies many signaling pathways, resulting in contradictory responses tha...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Canales, Jimena, Valenzuela, Manuel, Bravo, Jimena, Cerda-Opazo, Paulina, Jorquera, Carla, Toledo, Héctor, Bravo, Denisse, Quest, Andrew F. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368181/
https://ncbi.nlm.nih.gov/pubmed/28401064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00092
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