Bisperoxovandium (pyridin‐2‐squaramide) targets both PTEN and ERK1/2 to confer neuroprotection

BACKGROUND AND PURPOSE: We and others have shown that inhibiting phosphatase and tensin homolog deleted on chromosome 10 (PTEN) or activating ERK1/2 confer neuroprotection. As bisperoxovanadium compounds are well‐established inhibitors of PTEN, we designed bisperoxovandium (pyridin‐2‐squaramide) [bp...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Zhang, Zhi‐Feng, Chen, Juan, Han, Xin, Zhang, Ya, Liao, Hua‐Bao, Lei, Rui‐Xue, Zhuang, Yang, Wang, Ze‐Fen, Li, Zhiqiang, Chen, Jin‐Cao, Liao, Wei‐Jing, Zhou, Hai‐Bing, Liu, Fang, Wan, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368051/
https://ncbi.nlm.nih.gov/pubmed/28127755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13727
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