Tumor necrosis factor alpha derived from classically activated “M1” macrophages reduces interstitial cell of Cajal numbers

BACKGROUND: Delayed gastric emptying in diabetic mice and humans is associated with changes in macrophage phenotype and loss of interstitial cells of Cajal (ICC) in the gastric muscle layers. In diabetic mice, classically activated M1 macrophages are associated with delayed gastric emptying whereas...

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Bibliographic Details
Published in:Neurogastroenterol Motil
Main Authors: Eisenman, Seth T., Gibbons, Simon J., Verhulst, Pieter-Jan, Cipriani, Gianluca, Saur, Dieter, Farrugia, Gianrico
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367986/
https://ncbi.nlm.nih.gov/pubmed/27781339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12984
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