Protein tyrosine phosphatase PRL2 mediates Notch and Kit signals in early T cell progenitors

The molecular pathways regulating lymphoid priming, fate, and development of multipotent bone marrow hematopoietic stem and progenitor cells (HSPCs) that continuously feed thymic progenitors remain largely unknown. While Notch signal is indispensable for T cell specification and differentiation, the...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kobayashi, Michihiro, Nabinger, Sarah, Bai, Yunpeng, Yoshimoto, Momoko, Gao, Rui, Chen, Sisi, Yao, Chonghua, Dong, Yuanshu, Zhang, Lujuan, Rodriguez, Sonia, Yashiro-Ohtani, Yumi, Pear, Warren S., Carlesso, Nadia, Yoder, Mervin C., Kapur, Reuben, Kaplan, Mark H., Lacorazza, H Daniel, Zhang, Zhong-Yin, Liu, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367971/
https://ncbi.nlm.nih.gov/pubmed/28009085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2559
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