Protein tyrosine phosphatase PRL2 mediates Notch and Kit signals in early T cell progenitors

The molecular pathways regulating lymphoid priming, fate, and development of multipotent bone marrow hematopoietic stem and progenitor cells (HSPCs) that continuously feed thymic progenitors remain largely unknown. While Notch signal is indispensable for T cell specification and differentiation, the...

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Vydáno v:Stem Cells
Hlavní autoři: Kobayashi, Michihiro, Nabinger, Sarah, Bai, Yunpeng, Yoshimoto, Momoko, Gao, Rui, Chen, Sisi, Yao, Chonghua, Dong, Yuanshu, Zhang, Lujuan, Rodriguez, Sonia, Yashiro-Ohtani, Yumi, Pear, Warren S., Carlesso, Nadia, Yoder, Mervin C., Kapur, Reuben, Kaplan, Mark H., Lacorazza, H Daniel, Zhang, Zhong-Yin, Liu, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367971/
https://ncbi.nlm.nih.gov/pubmed/28009085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2559
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