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Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity1

Th22 cells are a major source of IL-22 and have been found at sites of infection and in a range of inflammatory diseases. However, their molecular characteristics and functional roles remain largely unknown due to our inability to generate and isolate pure populations. We developed a novel Th22 diff...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Plank, Maximilian W., Kaiko, Gerard E., Maltby, Steven, Weaver, Jessica, Tay, Hock L., Shen, Wei, Wilson, Mark S., Durum, Scott K., Foster, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367520/
https://ncbi.nlm.nih.gov/pubmed/28100680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601480
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