A Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation

Bioorthogonal labeling of antibodies enables the conjugation of compounds, such as small molecules or peptides, which expand targeting capacity or enhance cytotoxicity. Taking advantage of a cyclohexene sulfonamide compound that site-selectively labels Lys64 in human serum albumin (HSA), we demonstr...

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Udgivet i:Bioconjug Chem
Main Authors: Patterson, James T., Wilson, Henry D., Asano, Shigehiro, Nilchan, Napon, Fuller, Roberta P., Roush, William R., Rader, Christoph, Barbas, Carlos F.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367151/
https://ncbi.nlm.nih.gov/pubmed/27666414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00432
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