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Total Synthesis and Stereochemical Assignment of Nostosin B

Nostosins A and B were isolated from a hydrophilic extract of Nostoc sp. strain from Iran, which exhibits excellent trypsin inhibitory activity. Nostosin A was the most potent natural tripeptide aldehyde as trypsin inhibitor up to now. Both r- and s-2-hydroxy-4-(4-hydroxy-phenyl)butanoic acid (Hhpba...

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Bibliografiske detaljer
Udgivet i:Mar Drugs
Main Authors: Wang, Xiaoji, Feng, Junmin, Xu, Zhengshuang, Ye, Tao, Meng, Yi, Zhang, Zhiyu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367015/
https://ncbi.nlm.nih.gov/pubmed/28264450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15030058
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