Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

Hepatitis C virus (HCV) is a positive single-stranded RNA virus of enormous global health importance, with direct-acting antiviral therapies replacing an immunostimulatory interferon-based regimen. The dynamics of HCV positive and negative-strand viral RNAs (vRNAs) under antiviral perturbations have...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Ramanan, Vyas, Trehan, Kartik, Ong, Mei-Lyn, Luna, Joseph M., Hoffmann, Hans-Heinrich, Espiritu, Christine, Sheahan, Timothy P., Chandrasekar, Hamsika, Schwartz, Robert E., Christine, Kathleen S., Rice, Charles M., van Oudenaarden, Alexander, Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366982/
https://ncbi.nlm.nih.gov/pubmed/27128351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.04.020
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