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Rattusin structure reveals a novel defensin scaffold formed by intermolecular disulfide exchanges

Defensin peptides are essential for innate immunity in humans and other living systems, as they provide protection against infectious pathogens and regulate the immune response. Here, we report the solution structure of rattusin (RTSN), an α-defensin-related peptide, which revealed a novel C(2)-symm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Min, Hye Jung, Yun, Hyosuk, Ji, Sehyeon, Rajasekaran, Ganesan, Kim, Jae Il, Kim, Jeong-Sun, Shin, Song Yub, Lee, Chul Won
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366907/
https://ncbi.nlm.nih.gov/pubmed/28345637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45282
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