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BRI2 homodimerizes with the involvement of intermolecular disulfide bonds

Familial British and Familial Danish Dementia (FBD and FDD) are two dominantly inherited neurodegenerative diseases that present striking similarities with Alzheimer’s disease. The genetic defects underlying those dementias are mutations in the gene that encodes for BRI2 protein. Cleavage of mutated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsachaki, Maria, Ghiso, Jorge, Rostagno, Agueda, Efthimiopoulos, Spiros
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783720/
https://ncbi.nlm.nih.gov/pubmed/18440095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.03.004
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