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WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel

WT1 is a transcription factor which regulates the epithelial-mesenchymal balance during embryonic development and, if mutated, can lead to the formation of Wilms’ tumour, the most common paediatric kidney cancer. Its expression has also been reported in several adult tumour types, including breast c...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Artibani, Mara, Sims, Andrew H., Slight, Joan, Aitken, Stuart, Thornburn, Anna, Muir, Morwenna, Brunton, Valerie G., Del-Pozo, Jorge, Morrison, Linda R., Katz, Elad, Hastie, Nicholas D., Hohenstein, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366898/
https://ncbi.nlm.nih.gov/pubmed/28345629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45255
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