WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel

WT1 is a transcription factor which regulates the epithelial-mesenchymal balance during embryonic development and, if mutated, can lead to the formation of Wilms’ tumour, the most common paediatric kidney cancer. Its expression has also been reported in several adult tumour types, including breast c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Artibani, Mara, Sims, Andrew H., Slight, Joan, Aitken, Stuart, Thornburn, Anna, Muir, Morwenna, Brunton, Valerie G., Del-Pozo, Jorge, Morrison, Linda R., Katz, Elad, Hastie, Nicholas D., Hohenstein, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366898/
https://ncbi.nlm.nih.gov/pubmed/28345629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45255
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