Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion

Prolyl hydroxylase enzymes (PHDs) sense cellular oxygen upstream of hypoxia-inducible factor (HIF) signaling, leading to HIF degradation in normoxic conditions. In this study, we demonstrate that adipose PHD2 inhibition plays a key role in the suppression of adipocyte lipolysis. Adipose Phd2 gene ab...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Michailidou, Zoi, Morton, Nicholas M., Moreno Navarrete, José Maria, West, Christopher C., Stewart, Kenneth J., Fernández-Real, José Manuel, Schofield, Christopher J., Seckl, Jonathan R., Ratcliffe, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2015
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366882/
https://ncbi.nlm.nih.gov/pubmed/25377876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0233
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars