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Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.

An unusual pattern in a nucleic acid or protein sequence or a region of strong similarity shared by two or more sequences may have biological significance. It is therefore desirable to know whether such a pattern can have arisen simply by chance. To identify interesting sequence patterns, appropriat...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Karlin, S, Altschul, S F
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53667/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2315319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.6.2264
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