Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks.

We describe an approach to analyzing protein sequence databases that, starting from a single uncharacterized sequence or group of related sequences, generates blocks of conserved segments. The procedure involves iterative database scans with an evolving position-dependent weight matrix constructed f...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Tatusov, R L, Altschul, S F, Koonin, E V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12091
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