Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1(-/-) mouse model

BACKGROUND: Severe hyperbilirubinemia is toxic during central nervous system development. Prolonged and uncontrolled high levels of unconjugated bilirubin lead to bilirubin-induced neurological damage and eventually death by kernicterus. Bilirubin neurotoxicity is characterized by a wide array of ne...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Vodret, Simone, Bortolussi, Giulia, Jašprová, Jana, Vitek, Libor, Muro, Andrés F.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366125/
https://ncbi.nlm.nih.gov/pubmed/28340583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0838-1
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