Structure of nogalamycin bound to a DNA hexamer.

The anthracycline antibiotic nogalamycin, which binds to DNA, is composed of a planar aglycone substituted on each end to form an unusual dumbbell-shaped molecule. At one end nogalamycin contains an uncharged nogalose sugar and a methyl ester. At the other end nogalamycin contains a positively charg...

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Autores principales: Williams, L D, Egli, M, Qi, G, Bash, P, van der Marel, G A, van Boom, J H, Rich, A, Frederick, C A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC53659/
https://ncbi.nlm.nih.gov/pubmed/2315315
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