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Tenofovir Disoproxil Fumarate Is a New Substrate of ATP-Binding Cassette Subfamily C Member 11

Tenofovir disoproxil fumarate (TDF), a nucleotide reverse transcriptase inhibitor, after conversion to tenofovir (TFV), is mainly eliminated by glomerular filtration and active tubular secretion. The major adverse effect of tenofovir is nephrotoxicity; however, the exact mechanism remains poorly und...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Tun-Yhong, Wisith, Chinpaisal, Chatchai, Pamonsinlapatham, Perayot, Kaewkitichai, Sindchai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365707/
https://ncbi.nlm.nih.gov/pubmed/28167562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01725-16
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