Plasmidic qnr Genes Confer Clinical Resistance to Ciprofloxacin under Urinary Tract Physiological Conditions

Escherichia coli variants expressing plasmid-mediated qnr genes are usually susceptible to fluoroquinolones by standard susceptibility testing. Here we show that, under specific urinary tract physiological conditions, susceptible laboratory and clinical strains harboring qnr determinants become full...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Martín-Gutiérrez, Guillermo, Rodríguez-Martínez, José Manuel, Pascual, Álvaro, Rodríguez-Beltrán, Jerónimo, Blázquez, Jesús
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365700/
https://ncbi.nlm.nih.gov/pubmed/28096153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02615-16
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